Friday, January 20, 2017

CHINA'S NEW AIRCRAFT CARRIER HINTS AT THE FUTURE OF ITS NAVY

THE LIAONING CARRIED AT LEAST THREE HELICOPTERS, EIGHT FIGHTERS, THREE DESTROYERS, TWO FRIGATES, AND A REFUELING SHIP.
Liaoning aircraft carrier China
A month ago China revealed that its plane carrying warship Liaoning was prepared to begin operational administration. The nation's naval force gave evidence on Christmas Day, conveying its first transporter fight amass (CVBG) through the Miyako Straits, around Taiwan, and into the South China Sea, propelling and recuperating airplane en route.

The Liaoning conveyed no less than three Z-18 helicopters and eight J-15 warriors, and in addition two Type 052C (171) destroyers, one Type 052D destroyer, two Type 054A frigates (538, 556), a Type 903A refueling ship, and a Type 056 corvette.
Liaoning aircraft carrier China J-15 Fighter
A Full Set

With likely no less than a squadron of J-15 contenders (eight on the deck, more probable underneath), the Liaoning has a standout amongst the most intense non-American bearer avionics aggregates on the planet.

Looking ahead to 2030, the following Chinese transporter will probably look fundamentally the same as the Liaoning CVBG, with overhauled destroyers and frigates that give a more progressed layered safeguard and rocket strike framework. It will probably be joined by an arms stockpile of automatons.

And after that comes the atomic controlled bearers of the Type 003 Chinese plane carrying warship. The Type 003 itself would likely have a removal of around 90,000-100,000 tons and convey anyplace from between 70-100 helicopters and settled wing flying machine, and have various air ship lifts and a solitary island superstructure. With an atomic controlled reactor, the Type 003 could achieve speeds in abundance of 30 bunches. The reactors could likewise give the ability to electromagnetically helped dispatch framework (EMALS) launches (the previous ordinary Type 002 transporter may utilize steam slings). EMALS slings have enhanced effectiveness and are less support serious than steam launches.

Liaoning aircraft carrier China
A Silent and Loud Message

The Liaoning CVBG traveled through debated waters in the South China Seas on its first operational voyage.

The air gathering will probably still utilize J-15 warriors for multi-part purposes, alongside an electronic fighting mission variation. For committed air prevalence mission, the air gathering could likewise have fifth-era stealth contenders, in all probability navalized forms of either the J-31 or even the J20. The EMALS sling could permit the Type 003 to dispatch flying machine with a departure weight of up to 50 tons, including elevated tankers, airborne early cautioning air ship (particularly valuable to directing long range rockets against far off air ship), hostile to submarine fighting (ASW) planes, littler load planes and strike flying machine. Given Chinese enthusiasm for unmanned vehicles, the Type 003 could accompany a UAV for observation and surveillance. The Type 003's air gathering will likewise have helicopters for ASW and hunt and safeguard missions.

The CVBG's escort components will probably comprise of Type 055 destroyers and a future Chinese frigate (Type 057?) with a coordinated pole. The enhanced Type 055, redesigned from the present frames under development, would have coordinated electric impetus framework to increment installed control era for sensors and direct vitality weapons. It will probably additionally be furnished with over a hundred long-go hostile to air and surface assault rockets, notwithstanding conveying helicopters. Given Chinese enthusiasm for unmanned maritime vehicles, those surface warriors would likely convey UAVs, UUVs, and USVs for mine countermeasure. For submerged escort, the going with submarine would likely be a Type 095 atomic assault submarine, stealthier and more vigorously equipped than current Chinese assault water crafts.
Liaoning aircraft carrier China Type 094 SSBN

The Boomer and Carrier

A Type 094 SSBN, seen to one side of the Liaoning's skiramp, went with the Liaoning on its lady operational voyage. The huge battle force of the Liaoning CVBG would give it extra assurance against different dangers like submarines and ASW air ship.

Contingent upon the CVBG mission profile, land and/or water capable fighting boats like the Type 071 landing stage dock and landing helicopter docks be sent to help land Chinese marines and air rangers strengths.

A long time of operational experience are still expected to make the Liaoning, and whatever remains of the PLAN, prepared for battle and other escalated bearer operations. Yet, the PLA is currently off to a vital begin with the Liaoning, and they have greater arrangements for what's to come.

TECH FOUND IN YOUR CELL PHONE COULD CURE MOTION-SICKNESS AND SAVE LIVES

stabilizing gyroscope for boats
On unpleasant oceans, a watercraft's shaking can be more than uncomfortable—as "Deadliest Catch" member Johnathan Hillstrand told the Seattle Times after a near disaster, "man over the edge" is something you never need to listen. "We hear it excessively," Hillstrand stated, amid a season that had as of now observed three anglers die. In wet climate and white water, steadiness can involve life and demise.

That is the reason numerous vessels now utilize gyroscopic balancing out instruments.

Without anyone else, gyrators are not another innovation—a wiped out Frenchman who neglected to wind up distinctly a specialist developed them in the 1850s. Leon Foucault had a limited eye and detested school. "His wellbeing was fragile, his character mellow," composed an adolescence companion, "shy and not far reaching." He wanted to play with machines. His mom constrained him into medicinal classes, where he performed superior to anything anybody expected—until he saw his first blood and swooned.

Be that as it may, in 1851, Foucault had the thought he could demonstrate the Earth's pivot. In his storm cellar, he built a pendulum that could move in any bearing, set it swinging, and looked as it kept to a similar plane while the Earth moved underneath it. Researchers were so struck by the disclosure that he was made a request to rehash the test before the whole Paris Observatory.

It was a short stride from that point to the gyrator, Foucault's next creation to exhibit the movement of the Earth. A gyrator is a turning wheel, called the rotor, that pivots around a hub. The rotor is mounted between two rings, known as gimbals, that rotate around their own particular tomahawks. This implies when weight is applied on the gimbals, the rotor is unaffected, making it a valuable device to quantify compass headings and pitch, roll, or yaw points—helpful for mariners attempting to discover the skyline on a foggy morning, or in a rocket made a beeline for the ISS.

Gyrators are still utilized as a part of numerous imperative devices, similar to the Hubble Space Telescope, racecars, planes, and PDAs. (Ever consider how Pokemon Go's enlarged reality really functions? Your iPhone utilizes the camera and the telephone's whirligig to show a picture of a Pokemon as if it were in this present reality.)

In a vessel, the normal shaking of the water moves the turning whirligig, creating weight known as torc. "As the vessel rolls, the gyro tilts fore and toward the back," says Andrew Semprevivo, Vice President of Sales and Marketing for Seakeeper, the creator of one of these balancing out spinners. The stabilizers utilize the vitality delivered by pushing the turning spinner off its vertical pivot to rectify the watercraft's heel. It's essentially a similar rule behind a surfer conforming his body's position on his board to coordinate a wave's surface.

To show, here's a reenactment of how a little watercraft would weave without the settling gyrator:

Saturday, November 26, 2016

Immune Engineering





he doctors looking at Layla Richards saw a little girl with leukemia bubbling in her veins. She’d had bags and bags of chemotherapy and a bone marrow transplant. But the cancer still thrived. By last June, the 12-month-old was desperately ill. Her parents begged—wasn’t there anything?
There was. In a freezer at her hospital—Great Ormond Street, in London—sat a vial of white blood cells. The cells had been genetically altered to hunt and destroy leukemia, but the hospital hadn’t yet sought permission to test them. They were the most extensively engineered cells ever proposed as a therapy, with a total of four genetic changes, two of them introduced by the new technique of genome editing.
Where the technology stands, it's a pretty radical treatment.

The doctors hoped to make Layla a “special,” a patient who got the drug outside a clinical trial. It was a gamble, since the treatment had been tried only in mice. If it failed, the company’s stock and reputation could tank, and even if it succeeded, the company might get in trouble with regulators. “It was saving a life versus the chance of bad news,” Choulika says.Soon a doctor from Great Ormond was on the phone to Cellectis, a biotechnology company with French roots that is now located on the East Side of Manhattan. The company owned the cancer treatment, which it had devised using a gene-editing method called TALENs, a way of making cuts and fixes to DNA in living cells. “We got a call. The doctors said, ‘We’ve got a girl who is out of T cells and out of options,’” AndrĂ© Choulika, the CEO of Cellectis, remembers. “They wanted one of the vials made during quality-control testing.”
Cellectis began developing the treatment in 2011 after doctors in New York and Philadelphia reported that they’d found a way to gain control over T cells, the so-called killer cells of the immune system. They had shown that they could take T cells from a person’s bloodstream and, using a virus, add new DNA instructions to aim them at the type of blood cell that goes awry in leukemia. The technique has now been tested in more than 300 patients, with spectacular results, often resulting in complete remission. A dozen drug firms and biotechnology companies are now working to bring such a treatment to market.
Foreseeing this problem, Cellectis had set out to use gene editing to create a more highly engineered but ultimately simpler “universal” supply of T cells made from the blood of donors. The company would still add the new DNA, but it would also use gene editing to delete the receptor that T cells normally use to sniff out foreign-looking -molecules.
“The T cell has a huge potential for killing. But the thing you can’t do is inject T cells from Mr. X into Mr. Y,” Choulika says. “They’d recognize Mr. Y as ‘non-self’ and start firing off at everything, and the patient will melt down.” But if the T cells are stripped down with gene editing, like the ones that were sitting in Great Ormond’s freezer, that risk is mostly eliminated. Or so everyone hoped.
In November, Great Ormond announced that Layla was cured. The British press jumped on the heartwarming story of a brave kid and daring doctors. Accounts splashed on front pages sent Cellectis’s stock price shooting upward. Two weeks later, the drug companies Pfizer and Servier announced they would ante up $40 million to purchase rights to the treatment. 
Although many of the details of Layla’s case have yet to be disclosed, and some cancer experts say the role of the engineered T cells in her cure remains murky, her recovery pointed a spotlight on “immune engineering,” and on the way that advances in controlling and manipulating the immune system are leading to unexpected breakthroughs in cancer treatment. They also could lead to new treatments for HIV and autoimmune diseases like arthritis and multiple